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Articles científics destacats

Aquesta secció inclou una llista dels treballs científics més destacats de l'IMB-CNM publicats en revistes incloses al Science Citation Index (SCI), per any de publicació.

impedimetric_aptasensor
Novel impedimetric aptasensor for label-free detection of Escherichia coli O157:H7
Sergi Brosel-Oliu et al.

A novel impedance-based aptasensor for detection of E. coli O157:H7 is proposed. The limit of detection of the biosensor is around 102 cfu·mL-1 with a detection time of 30 minutes. The selectivity of the developed aptasensor is demonstrated in regard to other bacterial strains. Regeneration protocol for the aptasensor, to be employed more than once, has been developed
Sensors & Actuators: B. Chemical V. 255 P3 (2018) pp. 2988-2995. 

figura_ssr
Solid State Relay Solutions for Induction Cooking Applications based on Advanced Power Semiconductor Devices
M. Fernández et al

This paper focuses on providing an improved and efficient alternative to electromechanical relays (EMRs) in view of the growing demand characteristics for an effective power multiplexing in induction heating applications. A major analytical approach to the design and implementation of bidirectional switches (BDSs) based on different power semiconductor technologies is presented, including thorough static and dynamic characterizations. Emerging gallium nitride high-electron-mobility transistors (GaN HEMTs) and silicon carbide (SiC)-based devices are identified as potential candidates for the mentioned applications.
IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS, vol. 66, no. 3, March 2019, pp. 1832-1841

tim_image
Output Power and Gain Monitoring in RF CMOS Class A Power Amplifiers by Thermal Imaging
X. Perpiñà et al.

The viability of using off-chip single-shot imaging techniques for local thermal testing in integrated radio frequency (RF) power amplifiers (PAs) is analyzed. With this approach, the frequency response of the output power and power gain of a Class A RF PA is measured, also deriving information about the intrinsic operation of its transistors. To carry out this paper, the PA is heterodynally driven, and its electrical behavior is down converted into a lower frequency thermal field acquirable with an InfraRed lock-in thermography (IR-LIT) system. After discussing the theory, the feasibility of the proposed approach is demonstrated and assessed with thermal sensors monolithically integrated in the PA. As crucial advantages to RF-testing, this local approach is noninvasive and demands less complex instrumentation than the mainstream commercially available solutions.
IEEE Transactions on Instrumentation and Measurement

molecular_metabolism_web2
CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity
R. Rodríguez-Rodríguez et al.

Carnitine palmitoyltransferase 1C (CPT1C) is implicated in central regulation of energy homeostasis. Our aim was to investigate whether CPT1C in the ventromedial nucleus of the hypothalamus (VMH) is involved in the activation of brown adipose tissue (BAT) thermogenesis in the early stages of diet-induced obesity.
Molecular Metabolism.

nature_materials_masvidal
High-resolution mapping of infraslow cortical brain activity enabled by graphene microtransistors
Eduard Masvidal-Codina et al.

The paper shows that arrays of graphene microtransistors are used to record infraslow cortical brain activity. The devices may be useful for monitoring of brain physiology.
Nature Materials volume 18, pages 280–288 (2019).

biosensing_platform
The 3D impedimetric sensors as a tool for monitoring bacterial response to antibiotics
S. Brosel-Oliu et al.

The developed microbial sensor based on interdigitated electrode array (3D-IDEA) impedimetric transducer was employed in a biosensing platform especially designed to monitor the bacterial response to the antibiotic ampicillin. To facilitate immobilization of bacteria within the trenches and prevent their deposition on top of the barriers an important novelty is the use of polyIJN-isopropylmethacrylamide) p(NIPMAM) microgels working as antifouling agents, deposited on top of the barriers by microcontact printing.
Lab. Chip, 2019, vol.19. pp. 1436 – 1447.

graphabstract
Mimicking the Spike-Timing dependent plasticity in HfO2-based memristors at multiple times scales
M. Maestro-Izquierdo et al.

TiN/Ti/HfO2/W memristors have been investigated to mimic the spike-time dependent plasticity (STDP) of biological synapses at multiple time scales. For this purpose, a smart software tool has been implemented to control the instrumentation and to perform a dedicated ultra-fast pulsed characterization. Different time scales, from tens of milliseconds to hundreds of nanoseconds, have been explored to emulate the STDP learning rule in electronic synapses. The impact of such times on the synaptic weight potentiation and depression characteristics has also been discussed.
Microelectronic Engineering 215 (2019) 111014.

microfluidic
Microfluidic Modules with Integrated Solid-State Sensors for Reconfigurable Miniaturized Analysis Systems
Pablo Giménez-Gómez et al.

Modular microfluidic systems based on a new magnetic clamping approach, which enables both interconnection of microfluidic modules and reversible integration of solid-state sensors, is presented in this work. The system layout allows the easy assessment of the system fluidic performance by using optically transparent and low cost polymeric materials.
ACS Omega, 2019, 4 (4), pp 6192–6198.

0_graphical
Electric Field Gradients and Bipolar Electrochemistry effects on Neural Growth: A finite element study on immersed electroactive conducting electrode materials
Ll. Abad et al.

Implantable electrodes act with direct electrical contact although recent work has shown that electrostimulation is also possible through non-contact wireless settings, through the generation of dipoles at the borders of the material by bipolar electrochemistry. Finite element studies shown here with the same configuration that the experimental processes described, evidence voltage profiles in qualitative agreement with known bipolar effects, although with a clear difference between intercalation materials and metals. These observations may explain the differences in neural cell growth observed for various substrate material.
Electrochimica Acta

abad_physrevapp
Growth Monitoring With Submonolayer Sensitivity Via Real-Time Thermal-Conductance Measurements
P. Ferrando-Villalba et al

Growth monitoring during the early stages of vapor deposition is of prime importance to understand the growth process, the microstructure, and thus the overall layer properties. We demonstrate that phonons can be used as an extremely sensitive probe to monitor the real-time evolution of film microstructure during growth. For that purpose, a silicon nitride membrane-based sensor is fabricated to measure the in-plane thermal conductivity of thin film samples. Operating with the 3ω-Völklein method at low frequencies, the sensor shows an exceptional resolution down to Δ(κ⋅t)=0.065W/mKnm, enabling accurate measurements even in poor conductive samples.
Phys. Rev. Applied 12, 014007