A heart-on-a-chip to better understand the human heart's response to drugs
Researchers at IDIBELL and IMB-CNM have developed a new vascularized cardiac model—a chip integrated with living cardiac tissue generated from human stem cells—that could advance our understanding of cardiotoxicity, one of the main barriers currently facing drug development. The new model is emerging as an alternative to reduce the use of animal models and prevent the discarding of promising drugs due to an overestimation of their cardiac toxicity