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Institute of Microelectronics of Barcelona IMB-CNM   

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Micro and Nanotechnology research for you

  • IMB-CNM Microelectronics Research and Development centre in Spain

  • Research groups dedicated to the field of Micro and Nano Integrated Systems

  • Integrated Clean room for Micro and Nano fabrication

  • IMB-CNM scientific papers published in journals

  • Image IMB-CNM

Welcome to the IMB-CNM


Welcome to the web page of the Barcelona Microelectronics Institute of the National Microelectronics Centre-CSIC.

Micro/Nano electronics, Photonics and Smart Systems have been identified by the European Commission as a fundamental part of the KETS-Key Enabling Technologies, which are the basis for the improvement of the innovation capability of the European industry. These technologies have a high economic potential and the capability to contribute to solve the current societal challenges.

Electronic systems are part of our lives for several decades now. The evolution of microelectronics has enabled its introduction as an essential part of multiple products that can benefit any sector of the economy, by including properties such as a higher product intelligence or more sustainability.

The IMB-CNM aims to contribute to these goals with a high level set of researchers and facilities, unique in the South of Europe. Not only we can offer our know-how to collaborate with you on designing and fabricating new micro and nanoelectronics components, circuits and systems, but also we can provide you education and training at the different stages of your scientific or engineering career. IMB-CNM is a research centre belonging to CSIC, placed in Barcelona and, more specifically being part of the Campus of Excellence of the Universitat Autònoma de Barcelona (UAB), that is a cluster of scientific activity that may perfectly fit with your needs.

We thank you for visiting the web site of our institute and we hope that the R&D activities that we are doing can be of your interest. Please feel free to contact us for any collaboration or visit in which you may be thinking of.

News & Events

Thanks to the donation of 1,000 masks from the Chinese Students and Scholars Association.

The Chinese Students and Scholars Association has donated the IMB-CNM and other institutions some masks. Wenchao Duan is a PhD fellow at the ICMAB and IMB and he is member of this Association: "On the premise of respecting their wishes, the Association has donated masks mainly to hospitals, nursing homes, health departments and research institutes in Spain", he says.

 NEWS  2020-05-26 

Cover Vol. 10 Issue 5, May 2020 Nanomaterials. Internalization and Viability Studies of Suspended Nanowire Silicon Chips in HeLa Cells.

Suspended 3 × 3 × 0.5 µm3 silicon chips were fabricated with distinct physical morphologies including micrometric, micro- and nanometric, and solely nanometric features. The micro- and nanometric combination was produced by random nanowires grown on silicon. The nanometric chips were formed with self-sustaining structures of entangled nanowires. The chips were co-cultured in HeLa cells to investigate their toxicity and the effect of the morphology during cell internalization. Cell viability was demonstrated and results showed initial cell interaction with the chip nanometric features before internalization. Internalized chips with integrated nanowires may provide means of delivery into the cytosol.

 NEWS  2020-05-25 

El IMB-CNM, nuevo miembro de la red SECPHO ha hecho hoy su presentación en una jornada con otros miembros.

SECPhO es un cluster que agrupa empresas, centros tecnológicos y grupos de investigación en el sector de la fotónica y la óptica.

 NEWS  2020-05-22 

Silicon technologies against Covid-19

In the Clean Room of the Barcelona Microelectronics Institute (IMB-CNM-CSIC) scientists are developing devices for COVID-1 diagnostic sensors. This work is part of two projects: Convat , led by ICN2, and POC4CoV, co-led by the Institute of Advanced Chemistry of Catalonia (IQAC-CSIC) and the IMB-CNM, CSIC.

 NEWS  2020-04-12 

IMB-CNM talks: Development of SiC sensors for harsh environment applications - Sofia Otero

Online talk
17/04/2020 11:30 a.m.

 EVENTS  2020-04-09 

Recent publications

Tracking intracellular forces and mechanical property changes in mouse one-cell embryo development
Marta Duch, et al; Nat. Mater. (2020).We identify a program of forces and changes to the cytoplasmic mechanical properties required for mouse embryo development from fertilization to the first cell division. Injected, fully internalized chips responded to sperm decondensation and recondensation, and subsequent device behavior suggested a model for pronuclear convergence based on a gradient of effective cytoplasmic stiffness. The nanodevices reported reduced cytoplasmic mechanical activity during chromosome alignment and indicated that cytoplasmic stiffening occurred during embryo elongation, followed by rapid cytoplasmic softening during cell division. Forces greater than those inside muscle cells were detected. These results suggest that intracellular forces are part of a concerted program that is necessary for development at the origin of a new embryonic life.


Internalization and Viability Studies of Suspended Nanowire Silicon Chips in HeLa Cells
Sara Duran, et al; Nanomaterials 2020, 10(5), 893.Here, we propose the integration of silicon nanowires on cell internalizable chips in order to combine the functional features of both approaches. The cellular uptake in HeLa cells of silicon 3 µm × 3 µm nanowire-based chips, and the results were compared with those of non-nanostructured silicon chips. Chip internalization without affecting cell viability was achieved however, important cell behavior differences were observed. The first stage of cell internalization was favored by silicon nanowire interfaces with respect to bulk silicon. In addition, chips were found inside membrane vesicles, and some nanowires seemed to penetrate the cytosol, which opens the door to the development of silicon nanowire chips as future intracellular sensors and drug delivery systems.


Lanthanide Luminescence to Mimic Molecular Logic and Computing through Physical Inputs
M. A. Hernández‐Rodríguez, et al; Adv. Optical Mater. 2020, 2000312..The remarkable advances in molecular logic reported in the last decade demonstrate the potential of luminescent molecules for logical operations, a paradigm-changing concerning silicon-based electronics. Trivalent lanthanide (Ln3+) ions, with their characteristic narrow line emissions, long-lived excited states, and photostability under illumination, may improve the state-of-the-art molecular logical devices. Here, the use of monolithic silicon-based structures incorporating Ln3+ complexes for performing logical functions is reported. Contrary to chemical inputs, physical inputs may enable the future concatenation of distinct logical functions and reuse of the logical devices, a clear step forward toward input–output homogeneity that is precluding the integration of nowadays molecular logic devices.


A self-calibrating and multiplexed electrochemical lab-on-a-chip for cell culture analysis and high-resolution imaging
Pablo Giménez-Gómez et al.; Lab Chip, 2020, Advance Article.This paper presents a new tool that allows a self-calibrating and multiplexed electrochemical lab-on-a-chip (ME-LoC) for cell culture analysis and high-resolution imaging. The ME-LoC contains a complex network of micro-channels and micro-chambers that allow compartmentalization of the reference electrode cell seeding and proliferation without biofouling electrode reactivation and recalibration and multiple analyte detection, namely glucose and hydrogen peroxide concentrations, conductivity and ORP, as a way to monitor cell metabolism. Electrochemical analysis is completed with high-resolution imaging after labelling with fluorescent dyes. For its simplicity, integration, automation, compartmentalisation and microfluidic control, thist technology is a promising alternative for in vitro testing and organ-on-a-chip development in the near future.


Automated Determination of As(III) in Waters with an Electrochemical Sensor Integrated into a Modular Microfluidic System
Pablo Giménez-Gómez et al.; ACS Sensors, 2019, 4, 3156−3165. • Development of a robust electrochemical sensor integrated into a modular microfluidic system with the potential for on-site monitoring of inorganic As(III) species.
• Microfluidic system enabling the automatic sensor calibration, sample uptake, sample preconditioning and eventual As(III) detection.
• Linear system response to As(III) in a concentration range of 1−150 μg L−1, with a detection limit of 0.42 μg L−1 (below the threshold value of 10 μg L−1 set by WHO.
• System validated by measuring As(III) in tap water samples and samples from two Argentinean aquifers.


Impedimetric transducers based on interdigitated electrode arrays for bacterial detection
S.Brosel-Oliu et al.; A review, Anal.Chim.Acta, 2019, vol.1088, pp. 1-19. This review is focused on publications dealing with interdigitated electrodes as a transducer unit and different bacteria detection systems using these devices. The first part of the review deals with the impedance technique principles, paying special attention to the use of interdigitated electrodes, while the main part of this work is focused on applications ranging from bacterial growth monitoring to label-free specific bacteria detection.


Full Review William Hill