IMB-CNM talks: Three-dimensional interdigitated electrode arrays (3D-IDEA) for label-free detection of bacteria - Sergi Brosel
Sala de Actos Pepe Millán, IMB-CNM, Campus UAB.
08/06/2018 11:30 a.m.
Abstract: The use of impedimetric transducers based on interdigitated electrode arrays (IDEA) have been widely employed for different biosensing applications in the last years. A new transducer design with the presence of insulating barriers between electrode digits, named a three-dimensional interdigitated electrode array (3D-IDEA), shows considerable improvement in sensitivity compared with standard planar IDEA sensors. The functional mechanism of the device is based on registration of changes in conductivity at the surface of the barrier provoked by electrical charge redistribution caused by surface chemical reactions. The potential use of the developed device as a sensor transducer to detect various chemical and biochemical reactions has been previously demonstrated.
The presentation will be focused on how the surface modification of the 3D-IDEA impedance-based sensor with the immobilization of different biorecognition molecules (lectins, aptamers and peptides) allows to develop sensitive and label-free detection of different bacterial strains, as well as bacterial contaminants like endotoxins.